Researchers in the School of Chemistry and Biochemistry at Georgia Tech use imaging as a tool to study chemical and biological phenomena and work to develop new imaging methods with novel capabilities. Chemical and biological imaging is used to explore a wide range of topics including the treatment of cancer with nanoparticles, the chemical defenses of seaweed, and the catalytic role of mineral surfaces in the evolution of life.
This research is highly interdisciplinary, incorporating elements of physical chemistry, analytical chemistry, biochemistry, and materials science. The development of new imaging methods, which use elements of physical and analytical chemistry, includes time-resolved fluorescence microscopy, electron cryomicroscopy, and combined mass spectrometry-imaging systems. In addition, the core facilities located in IBB provide multiple confocal fluorescence microscopes, a two-photon fluorescence microscope, and MALDI mass spectrometry imaging for use by any interested researcher.
Faculty
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Biological imaging and spectroscopy; metal cluster fluorophores; fluorescent proteins; protein-protein interactions; novel imaging and spectroscopies; optically modulated fluorescence; statistics for multidimensional data analysis; antibacterial sensitivity; in vivo imaging
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bioinorganic chemistry; synthetic organic chemistry; coordination chemistry; organic photophysics; trace metal homeostasis; copper proteins; fluorescent probes; fluorescence imaging; x-ray fluorescence microscopy; live cell imaging; two-photon excitation microscopy
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Bioanalytical Mass Spectrometry: Ambient Sampling/Ionization & Molecular Imaging, Ion Mobility Spectrometry, Metabolomics, Pharmaceutical Forensics.
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Chemical biology, Organic chemistry, Click chemistry, Catalysis, Materials chemistry, Chemical biology; Organic chemistry; Polymer science; Biomaterials; Immunology; Protein nanoparticles; Medicinal chemistry; Antiviral agents; Combinatorial chemistry; Molecular evolution; SELEX; Cell targeting; Backscattering interferometry
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Bioanalytical mass spectrometry, Mass spectrometry imaging, Whole organ imaging, Metabolomics, Human microbiome analyses, Natural product biosynthesis, Environmental chemistry, Clinical microbiology
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Aquatic chemical ecology; Chemical signaling; Chemical communication; Marine natural products; Secondary metabolism; Drug discovery; Plankton ecology; Metabolomics
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Metallo-biochemistry, Metallo-chemical biology, Redox biology
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Structure & function of eukaryotic membrane proteins; membrane protein complexes; biophysics; cryo-EM; electron crystallography; 2D crystallization; image processing; inflammation; cancer
